Magister en Física Médica

Facultad de Física




  • Araceli Gago-Arias, Beatriz Sánchez-Nieto, Ignacio Espinoza, Christian P. Karger, Juan Pardo-Montero. Impact of different biologically-adapted radiotherapy strategies on tumor control evaluated with a tumor response model. PLOS ONE. 10.1371/journal.pone.0196310.
  • Beatriz Sánchez-Nieto; Maite Romero-Expósito; José Antonio Terrón; Leticia Irazola; Marta Paiusco; Elisabetta Cagni; Caterina Ghetti; Silvano Filice; Francisco Sánchez-Doblado. Intensity-modulated radiation therapy and volumetric modulated arc therapy versus conventional conformal techniques at high energy: Dose assessment and impact on second primary cancer in the out-of-field region. Reports of Practical Oncology and Radiotherapy.23 (2018) 251–259.


  • Dusan Racordon, Andres Valdivia, Gabriel Mingo, Rafaela Erices, Raul Aravena, Felice Santoro, Maria Loreto Bravo, Carolina Ramirez, Pamela Gonzalez, Alejandra Sandoval, Alfonso Gonzalez, Claudio Retamal, Marcelo Kogan, Sumie Kato, Mauricio Cuello, German Osorio, Francisco Nuarlart, Pedro Alvarez, María Araceli Gago-Arias, Daniella Fabri, Ignacio Espinoza, Beatriz Sanchez, Alejandro Corvalan, Mauricio Pinto, and Gareth Owen, 2017. Structural and functional identification of vasculogenic mimicry in vitro. Scientific Reports. 1;7(1):6985 (2017). doi:10.1038/s41598-017-07622-w

  • L. Irazola, J.A. Terrón, R. Bedogni, A. Pola, M. Lorenzoli, E. Jimenez-Ortega, A.R. Barbeiro, B. Sánchez-Nieto, F. Sánchez-Doblado. Neutron measurements in radiotherapy: A method to correct neutron sensitive devices for parasitic photon response. Applied Radiation and Isotopes 123 (2017) 32–35. Doi: 10.1016/j.apradiso.2016.12.060

  • B. Sánchez-Nieto, Maite Romero-Expósito, José A. Terrón, Francisco Sánchez-Doblado. Uncomplicated and Cancer-Free Control Probability (UCFCP): A new integral approach to treatment plan optimization in photon radiation therapy. Physica Medica: European Journal of Medical Physics. In press. DOI:
  • Irazola L, Terrón JA, Sánchez-Nieto B, Bedongi R and Sánchez-Doblado F. Peripheral neutron dose model upgrade and evaluation in 510 radiotherapy patients. EJCMP Phys Med, doi: 10.1016/j.ejmp.2017.03.018.
  • Technical Note: Parallel implementation of the EGSnrc Monte Carlo simulation of ionizing radiation transport using OpenMP. Doerner E, Caprile P. Med Phys. 2017 Dec;44(12):6672-6677. doi: 10.1002/mp.12642. Epub 2017 Nov 14. PMID: 29105093
  • Quality control in cone-beam computed tomography (CBCT) EFOMP-ESTRO-IAEA protocol (summary report). de Las Heras Gala H, Torresin A, Dasu A, Rampado O, Delis H, Hernández Girón I, Theodorakou C, Andersson J, Holroyd J, Nilsson M, Edyvean S, Gershan V, Hadid-Beurrier L, Hoog C, Delpon G, Sancho Kolster I, Peterlin P, Garayoa Roca J, Caprile P, Zervides C. Phys Med. 2017 Jul;39:67-72. doi: 10.1016/j.ejmp.2017.05.069. Epub 2017 Jun 9. PMID: 28602688


  •  Using a Tandem Pelletron accelerator to produce a thermal neutron beam for detector testing purposes. Applied Radiation And Isotopes. 2016;107:330-334.

  • A. Gago-Arias, I. Espinoza, B. Sánchez-Nieto and J. Pardo-Montero.  Modelling of radiation-induced cell death and re-oxygenation: Local versus global and instant versus delayed cell death. Phys. Med. Biol. 61 (2016) 1204–1216.

  • Doerner, Edgardo, and Paola Caprile. "Implementation of a double Gaussian source model for the BEAMnrc Monte Carlo code and its influence on small fields dose distributions." Journal of Applied Clinical Medical Physics 17.5 (2016).



  • M. R. Expósito, B. Sánchez-Nieto, J A. Terrón, M do Carmo Lopez, B C. Ferreira, D Grishchuk, C Sandín, S Moral-Sánchez, L Bragado-Álvarez, M Melchor, C Domingo, F Gómez and F. Sánchez-Doblado. Commissioning the neutron production of a linac: development of a clinical planning tool for second cancer risk estimation. Med. Phys. 42, 276 (2015)
  • I. Espinoza, P. Peschke, and C. P. Karger, “A voxel-based multiscale model to simulate the radiation response of hypoxic tumors,” Medical Physics, vol. 42, no. 1, pp. 90–102, 2015. 
  • B. Sánchez-Nieto , R. El-far, L. Irazola, M.Romero-Expósito, J.I. Lagares, J.C. Mateo, J.A. Terrón, and F. Sánchez DobladoAnalytical model for photon peripheral dose estimation in radiotherapy treatments. Biomed. Phys. Eng. Express 1 (2015) 045205. doi:10.1088/2057-1976/1/4/045205
  • Caprile, Paola, Günther H. Hartmann, and Edgardo Doerner. "Development and application of a dose verification tool using a small field model for TomoTherapy." Zeitschrift fuer Medizinische Physik 25.1 (2015): 48-57.
  • Gago-Arias, A.; Argüeso, P.; Aguiar ,P.; Gonzalez-Castaño, D.M.; Gómez, F.; Pardo-Montero, J. Characterization of tetramethylsilane for liquid-filled ionization dosimeters: Ion mobilities, free-ion yield and general recombination. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT. 785, pp. 170 - 174. 2015.
  • Gago-Arias, A.; Gonzalez-Castaño, D.M.; Gómez, F.; Peteiro, E.; Lodeiro, C.; Pardo-Montero, J. Development of an alanine dosimetry system for radiation dose measurements in the radiotherapy range. JOURNAL OF INSTRUMENTATION. 10, 2015.


  • Morales-Molina, L., Doerner, E., Danieli, C., & Flach, S. (2014). Resonant extended states in driven quasiperiodic lattices: Aubry-Andre localization by design. Physical Review A - Atomic, Molecular, and Optical Physics. 90(4);
  • L. Irazola, M. Lorenzoli, R. Bedogni, A. Pola, J.A. Terrón , B. Sánchez-Nieto, M.R. Expósito, J.I. Lagares, F. Sansaloni and F. Sanchez-Doblado A new online detector for estimation of peripheral neutron equivalent dose in organ. Med. Phys. 41, 112105 (2014);


  • Caprile, PF, Sánchez-Nieto, B, Pino, AM y Delgado, JF. Effects of heating rate and dose on trapping parameters of TLD-100 crystals. Health Physics. 104(2):218-223, 2013. DOI: 10.1097/HP.0b013e3182664111.
  • M. R. Expósito, B. Sánchez-Nieto, J. A. Terrón, Carles Domingo, F. Gómez, F. Sánchez-Doblado. Neutron contamination in radiotherapy: estimation of second cancers based on measurements in 1377 patients. Radiotherapy and Oncology. Radiotherapy and Oncology. 107:234-243, 2013.
  • I. Espinoza, CP Peschke, K. Karger. A model to simulate the oxygen distribution in hypoxic tumors for different vascular architectures. Med. Phys. 40 (8), 2013.
  • F.Lucic, B. Sánchez-Nieto, P. Caprile, G. Zelada and K. Goset. Dosimetric characterization and optimization of a customized Stanford total skin electron irradiation (TSEI) technique. Journal of Applied Clinical Medical Physics
  • Daniella Fabri, Valentina Zambrano, Amon Bhatia , Hugo Furtado , Helmar Bergmann, Markus Stock , Christoph Bloch , CarolaLûtgendorf-Caucig , Supriyanto Pawiro Dietmar Georg, Wolfgang Birkfellner, Michael Figl. A quantitative comparison of three deformable registration algorithms for compensation of interfractional organ motion in radiotherapy. Zeitschrift für Medizinische Physik. 23(4), 279-290. 2013.
  • Valentina Zambrano, Hugo Furtado, Daniella Fabri, et al. Performance validation of deformable image registration in the pelvic region. Journal of Radiation Research. 54, i120-i128.2013.


  • F Sánchez-Doblado, C Domingo, F Gómez, B Sánchez-Nieto et al. Methodology and benchmark dataset for radiotherapy real time assessment of patient neutron dose and application to a novel digital detector. Phys. Med. Biol. 57:6167-6191, 2012.
  • Sánchez-Nieto B, Goset K, Caviedes I, Delgado I and Córdova A. Predictive models for radio-induced pulmonary function changes after radiotherapy for breast cancer and lymphoma. Int. J. Radiat. Oncol. Biol. Phys. Vol 82(2):e257-e264, 2012.
  • E Doerner and G H Hartmann, Development and validation of a BEAMnrc component module for a miniature multileaf collimator, Phys. Med. Biol. 57(10):3093-3105, 2012.
  • Jakob Spoerk, Christelle Gendrin, Christelle Gendrin, Christoph Weber, Michael Figl, Supriyanto Ardjo Pawiro, Hugo Furtado, Daniella Fabri, Christoph Bloch, Helmar Bergmann, Eduard Gröller, Wolfgang Birkfellner. High-performance GPU-based rendering for real-time, rigid 2D/3D-image registration and motion prediction in radiation oncology. Zeitschrift für Medizinische Physik, 22, 1, 13-20, 2012.


  • Sarah L. Gulliford, Kerwyn Foo, Rachel C. Morgan, Edwin G. Aird, A. Margaret Bidmead, Helen Critchley, Philip M. Evans, Stefano Gianolini, W. Philip Mayles, A. Rollo Moore, Beatriz Sánchez-Nieto, Mike Partridge, Matthew R. Sydes, Steve Webb, David P. Dearnaley . Dose–Volume Constraints to Reduce Rectal Side Effects From Prostate Radiotherapy: Evidence from MRC RT01 Trial ISRCTN 47772397. Int. J. Radiat. Oncol. Biol. Phys. Vol. 76, No. 3, pp. 747–754, 2010. (This paper has been selected through the ASTRO CME selection process and by James Cox, M.D., editor of ASTRO's Red Journal, to be the feature article for an online ASTRO/Red Journal CME offering in March 2010. ASTRO will feature the article on the ASTRO website for their members, with accompanying online exam items, as an additional resource for attaining Category 1 CME credit).




Proceedings de conferencias

  • Expósito MR, Romero-Hermida MI, Terrón JA, Esposito D, Planes D, Lagares JI, Sánchez-Nieto, B, Amgarou K, Domingo C, Gómez F, Roselló J and F Sánchez-Doblado. Neutron contamination in medical linear accelerators operating at electron mode. In: Long M, editors WC 2012, IFMBE. Proceedings 39, Berlin: Springer. 1225-1228, 2012.
  • Gónzalez-Soto X, Amgarou K, Lagares JI, Expósito MR, Gómez F, Domingo C, Sánchez-Nieto B and Sánchez-Doblado F. Neutron distribution in radiotherapy treatment rooms. In: Long M, editors WC 2012, IFMBE Proceedings 39, Berlin:Springer. 1245-1737, 2012.
  • Gónzalez-Soto X, Expósito MR, Sánchez-Nieto B, Amgarou K, Lagares JI, Gómez F, Domingo C and Sánchez-Doblado F. Neutron spectra inside an adult and children anthropomorphic phantoms in high energy radiotherapy. In: Long M, editors WC 2012, IFMBE Proecedings 39, Berlin:Springer. 1145-1148, 2012.
  • Sánchez-Nieto B, Expósito MR, Terrón JA, Paiusco M, Cagni E, Ghetti C, Filice S, Grishchuk D, Mateos JC, Roselló J, Planes D, Esposito D, Nuñez L and Sánchez-Doblado F. The best prostate plan ever: a quantification of the therapeutic window. In: Long M, editors WC 2012, IFMBE Proceedings 39, Berlin:Springer.1735-1737, 2012.
  • Doerner, Edgardo. "Parallel processing implementation for the coupled transport of photons and electrons using OpenMP." Journal of Physics: Conference Series. Vol. 720. No. 1. IOP Publishing, 2016.


Abstracts de congresos


  • I. Liedtke-Grau, R.O. Floca, P. Peschke, I. Espinoza, C.P. Karger. Simulation of the radiation response of a hypoxic prostate tumor in the rat. ESTRO 35 Congress, Turín, Italia. 2016.
  • J. Grasmann, P. Caprile and D. Venencia. Dosimetric evaluation of the intrafractional respiratory motion effect, a phantom study. VII Latin American Congress on Medical Physics, XIII Argentine Congress on Medical Physics, ALFIM – SAFIM. Córdoba, Argentina, Septiembre 2016.
  • Edgardo Doerner, Beatriz Sánchez-Nieto, Ana María Cardona. "Simulación Monte Carlo de dosis periférica en tratamientos con Gamma Knife". 7º Congreso Latinoamericano de Física Médica ALFIM. 4 al 7 de Septiembre 2016, Villa Carlos Paz, Córdoba, Argentina. 
  • Edgardo Doerner, Paola Caprile. "Implementación de un modelo de fuente doble Gaussiana para el código Monte Carlo BEAMnrc y su influencia en distribuciones de dosis para campos pequeños". 7º Congreso Latinoamericano de Física Médica ALFIM. 4 al 7 de Septiembre 2016, Villa Carlos Paz, Córdoba, Argentina.
  • Doerner, Edgardo. "OpenMP parallelism for Monte Carlo simulations for particle transport using Intel Xeon Phi Coprocessors". 18th International Conference on the Use of Computers in Radiation Therapy. 27-30 June 2016, London UK.


  • E. Pena, P. Caprile, B. Sánchez-Nieto. SU-ET-308: Systematic Characterization of the Energy Response of Different LiF TLD Crystals for Dosimetry Applications. Med. Phys. 41 , 295. 2014
  • J. Tellez, R. Guzman, E. Doerner. Caracterización dosimétrica de haces de fotones con EGSNRC en campos pequeños colimadores de un MLC y MMLC."4tas Jornadas de Física Médica. Pucón-Chile 12-14 de nov. 2014.
  • E. Doerner. Implementación de cómputo paralelo del transporte acoplado de fotones y electrones utilizando OpenMP. XIX Simposio SOCHIFI, 26-28 de Noviembre, Concepción 2014.
  • I. Espinoza, P. Peschke, C.P. Karger. Simulation of the radiation response of hypoxic tumors. SU-E-J-273 Med. Phys. 41, AAPM Annual Meeting, Austin, Texas. 2014.
  • I. Espinoza, P. Peschke, C.P. Karger. Simulación de la respuesta a la radiación de tumores hipóxicos. 4tas Jornadas de Física Médica. Pucón-Chile 12-14 de nov. 2014.
  • E. Peña, P. Caprile, B. Sánchez.  Caracterización sistemática de la respuesta energética de diferentes cristales termoluminiscentes de LiF para aplicaciones dosimétricas. XIV Congreso Nacional, Sociedad Chilena de Radioterapia Oncológica.  Huilo Huilo,  Marzo de 2014.



  • Sánchez-Nieto, B.; Caprile, P.; Lagos, F.; Lucic, F. and Zelada, G. SUE-J-21: Entrance dose evaluation during KV-CBCT scans for different KVp and FOV settings.  Med. Phys. 40, 154. 2013.
  • P. Caprile, B. Sánchez-Nieto, G. Chorbadjian, C. Morales, F. Lucic and K.C. Goset. In-phantom measurements of accelerated partial irradiation and arc-therapy for breast cáncer. Aceptado, Congreso ESTRO Forum, Ginebra (Suiza) 2013.
  • Eduardo Cisternas Jiménez, Beatriz Sánchez Nieto, Edgardo Dörner. Simulación Monte Carlo de un sistema de rayos-X para tomografía computarizada de haces cónicos (CBCT). ALFIM, Guanacaste (Costa Rica) 2013.
  • Gabriela Chorbadjian, Beatriz Sánchez, Paola Caprile, Claudia Morales, Felipe Lucic. Evaluación dosimétrica del algoritmo de convolución/superposición en tratamientos de radioterapia para cáncer de mama. ALFIM, Guanacaste (Costa Rica)  2013.
  • F. Lagos, P. Caprile, B. Sánchez-Nieto, E. Doerner, G. Zeladas y E. Cisternas. Evaluación de la dosis de entrada en tomografía computada de haces cónicos de kilovoltaje (KVCBCT) para diferentes configuraciones de tamaño de campo (FOV) y parámetros del tubo. Aceptado, 4to Congreso de Radioquimioterapia y Braquiterapia y las 7ª Jornada de Física Médica 12-15 Junio, Córdoba (Argentina) 2013.
  • E. Doerner y P. Caprile. Desarrollo de un nuevo modelo para el estudio de la fuente de radiación de un linac utilizando el código BEAMnrc. Aceptado, 4to Congreso de Radioquimioterapia y Braquiterapia y las 7ª Jornada de Física Médica 12-15 Junio, Córdoba (Argentina) 2013.


  • Sánchez-Nieto B., Romero, MT, Terrón, JA, Paiusco, M, Cagni, E, Ghetti, C, Filice, S, Grishchuk, D, Mateos, JC, Roselló, J, Planes, D, Núñez, L and Sánchez-Doblado,TCP and NTCP: is that all?. Med. Phys. 39 (6): 3812, 2012.
  • Sánchez-Nieto B., Romero, MT, Sansaloni, F, Lagares, JI, Sánchez, P, Medrano, JC, Garayoa, J and Sánchez-Doblado, F. Modelling peripheral photon dose in tomotherapy treatments. Med. Phys. 39 (6): 3794, 2012.
  • P. Caprile, B. Sánchez-Nieto, A.M. Pino and J. F. Delgado. Kinetic parameters of TLD-100: dose and heating rate effects. Radiother. Oncol. 103, suppl1, S505; EP 1317, 2012.
  • M.R. Expósito, B. Sánchez-Nieto, et al. Experimental estimation of the second cáncer risk due to neutron contamination in radiotherapy treatments. Radiother. Oncol. 103, suppl1, S521; EP 1331, 2012.
  • B. Palma Fernández, M.R. Expósito, B. Sánchez-Nieto et al. Measurements of peripheral photon dose in conformal radiotherapy. Radiother. Oncol. 103, suppl1, S529; EP 1380,2012.
  • F. Sansaloni, M.R. Expósito, B. Sánchez-Nieto et al. Experimental determination of of peripheral photon dose in modern radiotherapy. Radiother. Oncol. 103, suppl1, S530; EP 1383, 2012.
  • V. Zambrano, D. Fabri, M. Stock, et al. A registration algorithmfor dose correction in radiation therapy-valiadation of deformable registration using phantoms. Radiother. Oncol. 102, suppl1, S59-S60.
  • V. Zambrano, D. Fabri, M. Stock, et al. A phantom study for the validation of an in-house deformable registration algorithm for dose accumulation. Radiother. Oncol. 103, suppl1, S338-S339.
  • Terrón JA, Sánchez-Nieto B, Expósito MR, Paiusco M, Cagni E, Ghetti C, Filice S, Grishchuk D, Mateos JC, Roselló J, Planes D, Esposito D, Romero R, Martinez J, Núñez L and Sánchez-Doblado F. Impact on biological ranking plan strategy of the neutron secondary cancer probability. Radiother Oncol. 103, suppl1, S576, 2012.
  • B. Palma Fernández, M.R. Expósito, B. Sánchez-Nieto et al. Measurements of peripheral photon dose in conformal radiotherapy. Radiother. Oncol. 103, suppl1, S576; EP 1494, 2012.
  • B. Sánchez-Nieto, M.R. Expóxito, et al. Including second cáncer malignancies into biological modelling. Radiother. Oncol. 103, suppl1, S527; EP 1496, 2012.


  • Daniella Fabri, Valentina Zambrano, Hugo Furtado. First results of the validation of an ITK implementation of piecewise non-rigid registration algorithm. Medizinsche Physik 2011.
  • Sánchez-Nieto B, Expósito MR et al. Dosimetría en tiempo real de la distribución de dosis periférica de neutrones en pacientes sometidos a tratamientos de radioterapia. Congreso Chileno de radioterapia, Huilo-Huilo (Chile) Noviembre 2011. 
  • Caprile PF, Sánchez-Nieto B, Pino AM y Delgado JF. Efectos de la tasa de calentamiento y dosis en los parámetros de atrapamiento de los cristales TLD-100. Congreso Chileno de radioterapia, Huilo-Huilo (Chile) Noviembre 2011.
  • M. Paiusco, E. Cagni, S. Filice, C. Ghetti, M. T. Romero Exposito, J. A. Terrón, B. Sánchez-Nieto, F. Sanchez-Doblado. Comparison of neutron contribution to peripheral doses in patients under 3D-CRT, IMRT and RapidArc treatments. Radiother. Oncol. 99, suppl1, S556 poster 1494, 2011.
  • Sanchez-Nieto B., et al. Why there are no evident threshold dose-volume parameters for the lung?: the impact of clinical factors and chemotherapy on pulmonary function tests. Radiother. Oncol. 99, suppl1, S353; poster 920, 2011.


  • Sanchez-Nieto B., Goset K, Delgado, I, Caviedes, I and Córdova A. Does V20 always matter? 29th ESTRO Meeting. Barcelona España, Septiembre 2010. Radiother. Oncol. 96, suppl1, S598, 2010.

Artículos en revistas (no ISI)

  • Sánchez-Nieto, B. El arte de la radioterapia. Revista Iberoamericana de física. Vol 7: 25-28, 2011.